Introducción

From June 2005 to January 2007, 28 consecutive patients: 8 Type 1 IDM (T1DM) and 20 type 2 IDM (T2IDM); who were receiving maximal medical therapy including insulin treatment for. Median time of disease for T2IDM patients was 13 years, without presence of pancreatic islet autoantibodies. After IRB approval and signed informed consent, bone marrow was harvested and ABMMC were isolated and infused directly into the pancreas via splenic artery using endovascular catheters. Glucose, glycosylated HbA1c and C peptide were measure before and after transplantation. HOMA2 Calculator v2.2 was used to calculated IR and % B (*if Glucose : 3.0 to 25.0 mmol/L and C-peptide : 0.2 to 3.5 nmol/L).